Crohns Disease has been getting a lot of news coverage lately here in the UK. From potential new ways to diagnose the disease to a sufferer taking the NHS to high court, I’ve learnt some new things about the disease, some of which I think you might be interested in too
The first thing that caught my attention is that scientists are close to developing a blood test for Crohn’s disease that could lead to new treatments. Up to half of patients who suffer with the disease have variations in a gene called NOD2, which helps control the immune system’s reaction by turning inflammation processes on and off.
Oxford University researchers have discovered the inflammation process is not properly switched off in these patients, as they don’t produce enough of a compound known as miR-29.The researchers say a blood test could detect levels of this compound, and giving miR-29 in drug form to restore it to the correct levels could be a treatment. They are looking to develop the test.
This could speed up the painfully slow time it takes to diagnose the disease and get sufferers the meds they need sooner.
The nest news piece I stumbled across this week was about a Crohn’s disease sufferer who is challenging what she claims is an ‘unlawful’ decision to refuse her funding for her eggs to be frozen before she undergoes chemotherapy.
Miss Rose, who was diagnosed with Crohn’s disease at the age of 14, faces ‘imminent’ bone marrow transplantation and chemotherapy - treatment she fears will render her infertile.
One theory is that Crohn’s is caused by the immune system attacking healthy bacteria in the gut. So by giving the patient a new immune system - through a bone marrow transplant - it is hoped that the disease can be cured.
To have a bone marrow transplant, stem cells are removed, high-dose chemotherapy is given to suppress the immune system - and stem cells are then returned.
Her claim was refused “on the basis that there is insufficient evidence to demonstrate effectiveness”
Crohns And Chemo ?!
I had no idea that Crohn’s Disease can be treated with chemo !?! I also didn’t know it was possible to give someone a NEW IMMUNE SYSTEM.
I thought that Remicade/Infliximab was the last possible, viable treatment drug that the UK had available to treat Crohns.
I found a small, probably unreliable source on the interwebs that claims that Remicade/Infliximab has now been reclassified as a chemotherapy drug. "It also falls into this category because it works by blocking proteins created by blood cells in your body".
Other than the usual pentasa/ azathioprine / infliximab ect.. what other meds are available that I’ve been kept in the dark about?
Is anyone here being treated for there crohns with chemo ? Is it helping?